Gain actionable insights into your
child’s genetics.

What is Picture genetic testing?

Picture^® genetic testing is offered by CBR^® (Cord Blood Registry^®) in partnership with Fulgent Genetics. There are 3 product levels designed to meet the needs of every family. These tests offer families the opportunity to have screening for up to 1,500+ genes that may impact a child’s risk of developing certain genetic conditions. Our most comprehensive test option also includes pharmacogenetic (PGx) testing which provides insight to how the body may respond to 100+ medications that may be prescribed throughout a person’s lifetime.

What are some of the conditions included in Picture genetic tests?

Picture genetic testing options include as many as 1,500+ genes, including genes related to certain blood disorders, metabolic disorders, cancers, heart conditions, epilepsy, and hearing and vision loss.¹³⁸ In the case of a positive result, meaning a potentially disease-causing genetic variant was identified, early detection may allow for faster diagnosis and treatment before symptoms appear.¹⁴⁴ All three testing options include conditions that may be treated with medication, dietary modification, or other therapies. Examples of these conditions include:

• G6PD deficiency is a common inherited condition that can cause mild-to-severe anemia when a child is exposed to fava beans, artificial blue food coloring, or foods with sulfites (a common preservative). If a family knows a child has this condition, avoidance of triggers may help children with the condition lead a healthy life.
• Lipid storage disorders are a group of conditions that do not allow the body to breakdown lipids, or fats, that we need. A subset of lipid storage disorders, called sphingolipidoses, can be identified with Picture genetic testing. Without treatment, these conditions can lead to the accumulation of fat in the body and cause damage to organs, like the liver and brain. Early diagnosis of these conditions can lead to treatment including medication or stem cell transplant.
• Spinal muscular atrophy (SMA) is a genetic disease that affects the nervous system. An FDA approved molecular therapy may improve symptoms. Starting treatment for SMA early, before symptoms appear, may help a child gain the greatest benefit from treatment.

What is pharmacogenetic (PGx) testing?

Pharmacogenetic (PGx) testing is a type of genetic testing that can tell us how someone breaks down or metabolizes certain medications. PGx testing can be helpful as part of personalized medicine -- a type of medical care in which treatment is customized for an individual patient. PGx results may provide information on how your child's body may potentially respond to certain drugs. Certain genetic variants may impact the metabolism of certain drugs, potentially making them more or less effective. Discussing these results with your child's healthcare provider may also potentially help avoid an adverse drug reaction (ADR), which is an unexpected, negative response to specific medications. PGx testing may help healthcare providers tailor what medications a person uses.¹⁴⁵

How do I order Picture genetic testing?

1. At the time of enrollment, expecting families enrolling with CBR for newborn stem cell preservation have the option to purchase Picture genetic testing.
2. If you order a Picture genetic test, the kit will be shipped to your home after the birth of your child. This kit includes simple step-by-step instructions to help you with the cheek swab process.
3. Once you receive the genetic testing kit, create a Picture Portal account with our genetic testing partner, Fulgent, at www.picturegenetics.com/portal/start-my-test/cbr.
4. Activate your test kit in your Picture Portal account using the activation code inside the test kit. Complete the informed consent step and answer a few questions about family health history and the child who will be tested.
5. Before starting the collection, read the instructions in the Genetic Test guide carefully and completely, making sure to follow each step provided.
6. Collect your child’s sample using the buccal swab(s) included inside the test kit. Once you have collected your child’s sample(s), return them to the kit and send them to the Picture lab using the pre-paid shipping envelope inside the kit.
7. Fulgent sequences and analyzes your child’s DNA at their advanced CLIA-certified lab. You can track the status of your child’s test on your Picture Portal account. You should receive the test results approximately three to five weeks after Picture receives your child’s sample in the mail.
8. Once the analysis is complete, your child’s genetic testing report will be available on your Picture Portal account. You will receive an email when the test results are ready.
9. After you receive your results, you can contact CBR’s Clinical Team at 1.888.267.3256 or at genetictest@cordblood.com with questions about your child’s Picture genetic test results.

What is the cost of Picture genetic testing?

See cordblood.com/enroll.