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The science behind newborn stem cells

Our services

Cord blood

Contains hematopoietic stem cells (HSCs), the building blocks of the blood and immune systems, with a 30-year history of saving lives106

Cord tissue

Contains mesenchymal stem cells (MSCs), endothelial stem cells, and epithelial stem cells, with additional treatment options in regenerative medicine109

Newborn stem cells by the numbers

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80+ conditions

Newborn stem cells found in cord blood are currently being used in transplant medicine to treat over 80 conditions, including certain cancers, blood disorders, and metabolic disorders.34

45,000+ transplants

Cord blood has been used in more than 40,000 stem cell transplants worldwide, from both public donor and private family banks, to help rebuild healthy blood and immune systems.106

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500+ clinical trials

Over 500 clinical trials are in progress worldwide studying cord blood and cord tissue’s role in advancing transplant medicine along with their potential applications in regenerative medicine.

100% chance

Your baby is always a 100% match to their own newborn stem cells, while full siblings have up to a 75% chance of being at least a partial genetic match.

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80%+ samples used in regenerative therapies

More than 80% of the cord blood used by CBR client families has been for experimental regenerative medicine applications, like cerebral palsy and autism.138

The transformative power of regenerative medicine

Newborn stem cells are currently being studied to determine their unique role in potentially regenerating or facilitating the repair of cells.

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Cord blood

Hematopoietic stem cells (HSCs) have the potential to:

  • Help improve organ and tissue damage caused by age, disease, or trauma108
  • Slow the progression of degenerative disease108
  • Be used in gene therapy treatments135-136

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Cord tissue

Mesenchymal stem cells (MSCs) have the potential to:

  • Reduce inflammation107
  • Treat burns, wounds, vascular damage, and respiratory complications due to COVID-19133
  • Modulate the immune system to help improve autoimmune disorders107,108

Areas of research within regenerative medicine

  • Lupus
  • Type 1 Diabetes
  • Bowel inflammation
  • Heart disease
  • Vascular damage
  • Damage from heart attack
  • Stroke
  • Cerebral palsy
  • HIE
  • Liver disease
  • Lung disease
  • Reproductive-related conditions
  • Wounds
  • Osteoarthritis
  • Spinal cord injury
  • Bone nonunion
  • Parkinson’s
  • Alzheimer’s disease
  • ALS

The impact of transplant medicine today

Cord blood is a source of newborn stem cells that is currently being used in transplant medicine to replace damaged blood and immune systems with healthy cells.

Proven transplant medicine uses:

Blood disorders

  • Acute Myelofibrosis
  • Agnogenic Myeloid Metaplasia (Myelofibrosis)
  • Amyloidosis
  • Aplastic Anemia (Severe)
  • Beta Thalassemia Major
  • Blackfan-Diamond Anemia
  • Congenital Amegakaryocytic Thrombocytopenia (CAT)
  • Congenital Cytopenia
  • Congenital Dyserythropoietic Anemia
  • Dyskeratosis Congenita
  • Essential Thrombocythemia
  • Fanconi Anemia
  • Glanzmann’s Thrombasthenia
  • Myelodysplastic Syndrome
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)
  • Polycythemia Vera
  • Pure Red Cell Aplasia
  • Refractory Anemia with Excess Blasts in Transition (RAEB-T)
  • Refractory Anemia with Ringed Sideroblasts (RARS)
  • Shwachman-Diamond Syndrome
  • Sickle Cell Disease

Cancers

  • Acute Biphenotypic Leukemia
  • Acute Lymphocytic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Acute Undifferentiated Leukemia
  • Adult T Cell Leukemia/Lymphoma
  • Chronic Active Epstein Barr
  • Chronic Lymphocytic Leukemia (CLL)
  • Chronic Myelogenous Leukemia (CML)
  • Ewing Sarcoma
  • Hodgkin’s Lymphoma
  • Juvenile Chronic Myelogenous Leukemia (JCML)
  • Juvenile Myelomonocytic Leukemia (JMML)
  • Myeloid/Natural Killer (NK) Cell PrecursorAcute Leukemia
  • Non-Hodgkin’s Lymphoma
  • Prolymphocytic Leukemia
  • Plasma Cell Leukemia
  • Chronic Myelomonocytic Leukemia (CMML)
  • Leukocyte Adhesion Deficiency
  • Multiple Myeloma
  • Neuroblastoma
  • Rhabdomyosarcoma
  • Thymoma (Thymic Carcinoma)
  • Waldenstrom’s Macroglobulinemia
  • Wilms Tumor

Immune disorders

  • Adenosine Deaminase Deficiency (SCID)
  • Bare Lymphocyte Syndrome (SCID)
  • Chediak-Higashi Syndrome (SCID)
  • Chronic Granulomatous Disease
  • Congenital Neutropenia
  • DiGeorge Syndrome
  • Evans Syndrome
  • Fucosidosis
  • Hemophagocytic Lymphohistiocytosis (HLH)
  • Hemophagocytosis Langerhans’ Cell Histiocytosis (Histiocytosis X)
  • IKK Gamma Deficiency (NEMO Deficiency)
  • Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) Syndrome
  • Kostmann Syndrome (SCID)
  • Myelokathexis
  • Omenn Syndrome (SCID)
  • Phosphorylase Deficiency (SCID)
  • Purine Nucleoside (SCID)
  • Reticular Dysgenesis (SCID)
  • Severe Combined Immunodeficiency Diseases (SCID)
  • Thymic Dysplasia
  • Wiskott-Aldrich Syndrome
  • X-linked Agammaglobulinemia
  • X-Linked Lymphoproliferative Disorder
  • X-Linked Hyper IgM Syndrome

Metabolic disorders

  • Congenital Erythropoietic Porphyria (Gunther Disease)
  • Gaucher Disease
  • Hunter Syndrome (MPS-II)
  • Hurler Syndrome (MPS-IH)
  • Krabbe Disease
  • Lesch-Nyhan Syndrome
  • Mannosidosis
  • Maroteaux-Lamy Syndrome (MPS-VI)
  • Metachromatic Leukodystrophy
  • Mucolipidosis II (I-cell Disease)
  • Neuronal Ceroid Lipofuscinosis (Batten Disease)
  • Niemann-Pick Disease
  • Sandhoff Disease
  • Sanfilippo Syndrome (MPS-III)
  • Scheie Syndrome (MPS-IS)
  • Sly Syndrome (MPS-VII)
  • Tay Sachs
  • Wolman Disease
  • X-Linked Adrenoleukodystrophy
  • Acute Myelofibrosis
  • Agnogenic Myeloid Metaplasia (Myelofibrosis)
  • Amyloidosis
  • Aplastic Anemia (Severe)
  • Beta Thalassemia Major
  • Blackfan-Diamond Anemia
  • Congenital Amegakaryocytic Thrombocytopenia (CAT)
  • Congenital Cytopenia
  • Congenital Dyserythropoietic Anemia
  • Dyskeratosis Congenita
  • Essential Thrombocythemia
  • Fanconi Anemia
  • Glanzmann’s Thrombasthenia
  • Myelodysplastic Syndrome
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)
  • Polycythemia Vera
  • Pure Red Cell Aplasia
  • Refractory Anemia with Excess Blasts in Transition (RAEB-T)
  • Refractory Anemia with Ringed Sideroblasts (RARS)
  • Shwachman-Diamond Syndrome
  • Sickle Cell Disease
  • Acute Biphenotypic Leukemia
  • Acute Lymphocytic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Acute Undifferentiated Leukemia
  • Adult T Cell Leukemia/Lymphoma
  • Chronic Active Epstein Barr
  • Chronic Lymphocytic Leukemia (CLL)
  • Chronic Myelogenous Leukemia (CML)
  • Ewing Sarcoma
  • Hodgkin’s Lymphoma
  • Juvenile Chronic Myelogenous Leukemia (JCML)
  • Juvenile Myelomonocytic Leukemia (JMML)
  • Myeloid/Natural Killer (NK) Cell PrecursorAcute Leukemia
  • Non-Hodgkin’s Lymphoma
  • Prolymphocytic Leukemia
  • Plasma Cell Leukemia
  • Chronic Myelomonocytic Leukemia (CMML)
  • Leukocyte Adhesion Deficiency
  • Multiple Myeloma
  • Neuroblastoma
  • Rhabdomyosarcoma
  • Thymoma (Thymic Carcinoma)
  • Waldenstrom’s Macroglobulinemia
  • Wilms Tumor
  • Adenosine Deaminase Deficiency (SCID)
  • Bare Lymphocyte Syndrome (SCID)
  • Chediak-Higashi Syndrome (SCID)
  • Chronic Granulomatous Disease
  • Congenital Neutropenia
  • DiGeorge Syndrome
  • Evans Syndrome
  • Fucosidosis
  • Hemophagocytic Lymphohistiocytosis (HLH)
  • Hemophagocytosis Langerhans’ Cell Histiocytosis (Histiocytosis X)
  • IKK Gamma Deficiency (NEMO Deficiency)
  • Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) Syndrome
  • Kostmann Syndrome (SCID)
  • Myelokathexis
  • Omenn Syndrome (SCID)
  • Phosphorylase Deficiency (SCID)
  • Purine Nucleoside (SCID)
  • Reticular Dysgenesis (SCID)
  • Severe Combined Immunodeficiency Diseases (SCID)
  • Thymic Dysplasia
  • Wiskott-Aldrich Syndrome
  • X-linked Agammaglobulinemia
  • X-Linked Lymphoproliferative Disorder
  • X-Linked Hyper IgM Syndrome
  • Congenital Erythropoietic Porphyria (Gunther Disease)
  • Gaucher Disease
  • Hunter Syndrome (MPS-II)
  • Hurler Syndrome (MPS-IH)
  • Krabbe Disease
  • Lesch-Nyhan Syndrome
  • Mannosidosis
  • Maroteaux-Lamy Syndrome (MPS-VI)
  • Metachromatic Leukodystrophy
  • Mucolipidosis II (I-cell Disease)
  • Neuronal Ceroid Lipofuscinosis (Batten Disease)
  • Niemann-Pick Disease
  • Sandhoff Disease
  • Sanfilippo Syndrome (MPS-III)
  • Scheie Syndrome (MPS-IS)
  • Sly Syndrome (MPS-VII)
  • Tay Sachs
  • Wolman Disease
  • X-Linked Adrenoleukodystrophy
Pie charts for Transplant indications and Regenerative indications

How CBR Clients have used their samples138

  • CBR has released more cord blood samples intended for medical use than any other family bank.‡
  • ‡ If information was not available on company website, data was based on the best information available.

CBR clinical trials and stem cell research

Successful treatments have paved the way for further research, and today, FDA-regulated clinical trials are exploring the use of a child’s own newborn stem cells for conditions that currently have no cure.36 Potential treatments being evaluated today include:

A physician’s perspective

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“There are only two things that (you can) potentially buy your new baby that are lifesaving: One is a good car seat, and the other is cord blood.”

Dr. Marra Francis, OB/GYN

CBR Medical Consultant

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“Just like we didn't envision the powers of computers thirty years ago, we may not be seeing all the uses of cord blood yet.”

Dr. LeeAnn Jensen, Immunologist

National Institutes of Health

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“A really exciting area that's just now in the basic science lab is the area where stem cells… can be used for going over to muscle cells like your heart muscle if you had a heart attack… Hopefully, in 20 or 30 or 40 years… these might be potential applications for stem cells, including umbilical cord blood stem cells.”

Dr. Stanton Goldman, Pediatric Hematologist Oncologist and Stem Cell Transplant Physician

Medical City — Dallas, TX

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“Stem cell technology is evolving rapidly, offering innovative treatments where none previously existed. We get one opportunity to bank a child's stem cells that could be lifesaving one day. Why would we choose to discard them?”

Tricia Shimer MD, PA, Comprehensive Women’s Care

Dallas, TX

Have more questions?

Our Newborn Stem Cell Educators would love to help!

888.932.6568
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