Male laboratory technician opening cryogenics tank.

The science behind newborn stem cells

Our services

Cord blood

Contains hematopoietic stem cells (HSCs), the building blocks of the blood and immune systems, with a 30-year history of saving lives¹⁰⁶

Cord tissue

Contains mesenchymal stem cells (MSCs), endothelial stem cells, and epithelial stem cells, with additional treatment options in regenerative medicine¹⁰⁹

Newborn stem cells by the numbers

80+ conditions

Newborn stem cells found in cord blood are currently being used in transplant medicine to treat over 80 conditions, including certain cancers, blood disorders, and metabolic disorders.³⁴

45,000+ transplants

Cord blood has been used in more than 40,000 stem cell transplants worldwide, from both public donor and private family banks, to help rebuild healthy blood and immune systems.¹⁰⁶

500+ clinical trials

Over 500 clinical trials are in progress worldwide studying cord blood and cord tissue’s role in advancing transplant medicine along with their potential applications in regenerative medicine.

100% chance

Your baby is always a 100% match to their own newborn stem cells, while full siblings have up to a 75% chance of being at least a partial genetic match.

An image of a green circle with a white circle in the middle.

80%+ samples used in regenerative therapies

More than 80% of the cord blood used by CBR client families has been for experimental regenerative medicine applications, like cerebral palsy and autism.¹³⁸

The transformative power of regenerative medicine

Newborn stem cells are currently being studied to determine their unique role in potentially regenerating or facilitating the repair of cells.

Cord blood

Hematopoietic stem cells (HSCs) have the potential to:

Help improve organ and tissue damage caused by age, disease, or trauma¹⁰⁸
Slow the progression of degenerative disease¹⁰⁸
Be used in gene therapy treatments^135-136

Cord tissue

Mesenchymal stem cells (MSCs) have the potential to:

Reduce inflammation¹⁰⁷
Treat burns, wounds, vascular damage, and respiratory complications due to COVID-19¹³³
Modulate the immune system to help improve autoimmune disorders^107,108

Areas of research within regenerative medicine

Lupus
Type 1 Diabetes
Bowel inflammation

Heart disease
Vascular damage
Damage from heart attack

Stroke
Cerebral palsy
HIE

Liver disease
Lung disease
Reproductive-related conditions
Wounds

Osteoarthritis
Spinal cord injury
Bone nonunion

Parkinson’s
Alzheimer’s disease
ALS

The impact of transplant medicine today

Cord blood is a source of newborn stem cells that is currently being used in transplant medicine to replace damaged blood and immune systems with healthy cells.

Proven transplant medicine uses:

Blood disorders

Acute Myelofibrosis
Agnogenic Myeloid Metaplasia (Myelofibrosis)
Amyloidosis
Aplastic Anemia (Severe)
Beta Thalassemia Major
Blackfan-Diamond Anemia
Congenital Amegakaryocytic Thrombocytopenia (CAT)
Congenital Cytopenia
Congenital Dyserythropoietic Anemia
Dyskeratosis Congenita
Essential Thrombocythemia
Fanconi Anemia
Glanzmann’s Thrombasthenia
Myelodysplastic Syndrome
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Polycythemia Vera
Pure Red Cell Aplasia
Refractory Anemia with Excess Blasts in Transition (RAEB-T)
Refractory Anemia with Ringed Sideroblasts (RARS)
Shwachman-Diamond Syndrome
Sickle Cell Disease

Cancers

Acute Biphenotypic Leukemia
Acute Lymphocytic Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Acute Undifferentiated Leukemia
Adult T Cell Leukemia/Lymphoma
Chronic Active Epstein Barr
Chronic Lymphocytic Leukemia (CLL)
Chronic Myelogenous Leukemia (CML)
Ewing Sarcoma
Hodgkin’s Lymphoma
Juvenile Chronic Myelogenous Leukemia (JCML)
Juvenile Myelomonocytic Leukemia (JMML)
Myeloid/Natural Killer (NK) Cell PrecursorAcute Leukemia
Non-Hodgkin’s Lymphoma
Prolymphocytic Leukemia
Plasma Cell Leukemia
Chronic Myelomonocytic Leukemia (CMML)
Leukocyte Adhesion Deficiency
Multiple Myeloma
Neuroblastoma
Rhabdomyosarcoma
Thymoma (Thymic Carcinoma)
Waldenstrom’s Macroglobulinemia
Wilms Tumor

Immune disorders

Adenosine Deaminase Deficiency (SCID)
Bare Lymphocyte Syndrome (SCID)
Chediak-Higashi Syndrome (SCID)
Chronic Granulomatous Disease
Congenital Neutropenia
DiGeorge Syndrome
Evans Syndrome
Fucosidosis
Hemophagocytic Lymphohistiocytosis (HLH)
Hemophagocytosis Langerhans’ Cell Histiocytosis (Histiocytosis X)
IKK Gamma Deficiency (NEMO Deficiency)
Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) Syndrome
Kostmann Syndrome (SCID)
Myelokathexis
Omenn Syndrome (SCID)
Phosphorylase Deficiency (SCID)
Purine Nucleoside (SCID)
Reticular Dysgenesis (SCID)
Severe Combined Immunodeficiency Diseases (SCID)
Thymic Dysplasia
Wiskott-Aldrich Syndrome
X-linked Agammaglobulinemia
X-Linked Lymphoproliferative Disorder
X-Linked Hyper IgM Syndrome

Metabolic disorders

Congenital Erythropoietic Porphyria (Gunther Disease)
Gaucher Disease
Hunter Syndrome (MPS-II)
Hurler Syndrome (MPS-IH)
Krabbe Disease
Lesch-Nyhan Syndrome
Mannosidosis
Maroteaux-Lamy Syndrome (MPS-VI)
Metachromatic Leukodystrophy
Mucolipidosis II (I-cell Disease)
Neuronal Ceroid Lipofuscinosis (Batten Disease)
Niemann-Pick Disease
Sandhoff Disease
Sanfilippo Syndrome (MPS-III)
Scheie Syndrome (MPS-IS)
Sly Syndrome (MPS-VII)
Tay Sachs
Wolman Disease
X-Linked Adrenoleukodystrophy

Acute Myelofibrosis
Agnogenic Myeloid Metaplasia (Myelofibrosis)
Amyloidosis
Aplastic Anemia (Severe)
Beta Thalassemia Major
Blackfan-Diamond Anemia
Congenital Amegakaryocytic Thrombocytopenia (CAT)
Congenital Cytopenia
Congenital Dyserythropoietic Anemia
Dyskeratosis Congenita
Essential Thrombocythemia
Fanconi Anemia
Glanzmann’s Thrombasthenia
Myelodysplastic Syndrome
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Polycythemia Vera
Pure Red Cell Aplasia
Refractory Anemia with Excess Blasts in Transition (RAEB-T)
Refractory Anemia with Ringed Sideroblasts (RARS)
Shwachman-Diamond Syndrome
Sickle Cell Disease

Acute Biphenotypic Leukemia
Acute Lymphocytic Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Acute Undifferentiated Leukemia
Adult T Cell Leukemia/Lymphoma
Chronic Active Epstein Barr
Chronic Lymphocytic Leukemia (CLL)
Chronic Myelogenous Leukemia (CML)
Ewing Sarcoma
Hodgkin’s Lymphoma
Juvenile Chronic Myelogenous Leukemia (JCML)
Juvenile Myelomonocytic Leukemia (JMML)
Myeloid/Natural Killer (NK) Cell PrecursorAcute Leukemia
Non-Hodgkin’s Lymphoma
Prolymphocytic Leukemia
Plasma Cell Leukemia
Chronic Myelomonocytic Leukemia (CMML)
Leukocyte Adhesion Deficiency
Multiple Myeloma
Neuroblastoma
Rhabdomyosarcoma
Thymoma (Thymic Carcinoma)
Waldenstrom’s Macroglobulinemia
Wilms Tumor

Adenosine Deaminase Deficiency (SCID)
Bare Lymphocyte Syndrome (SCID)
Chediak-Higashi Syndrome (SCID)
Chronic Granulomatous Disease
Congenital Neutropenia
DiGeorge Syndrome
Evans Syndrome
Fucosidosis
Hemophagocytic Lymphohistiocytosis (HLH)
Hemophagocytosis Langerhans’ Cell Histiocytosis (Histiocytosis X)
IKK Gamma Deficiency (NEMO Deficiency)
Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) Syndrome
Kostmann Syndrome (SCID)
Myelokathexis
Omenn Syndrome (SCID)
Phosphorylase Deficiency (SCID)
Purine Nucleoside (SCID)
Reticular Dysgenesis (SCID)
Severe Combined Immunodeficiency Diseases (SCID)
Thymic Dysplasia
Wiskott-Aldrich Syndrome
X-linked Agammaglobulinemia
X-Linked Lymphoproliferative Disorder
X-Linked Hyper IgM Syndrome

Congenital Erythropoietic Porphyria (Gunther Disease)
Gaucher Disease
Hunter Syndrome (MPS-II)
Hurler Syndrome (MPS-IH)
Krabbe Disease
Lesch-Nyhan Syndrome
Mannosidosis
Maroteaux-Lamy Syndrome (MPS-VI)
Metachromatic Leukodystrophy
Mucolipidosis II (I-cell Disease)
Neuronal Ceroid Lipofuscinosis (Batten Disease)
Niemann-Pick Disease
Sandhoff Disease
Sanfilippo Syndrome (MPS-III)
Scheie Syndrome (MPS-IS)
Sly Syndrome (MPS-VII)
Tay Sachs
Wolman Disease
X-Linked Adrenoleukodystrophy

Pie charts for Transplant indications and Regenerative indications

How CBR Clients have used their samples¹³⁸

CBR has released more cord blood samples intended for medical use than any other family bank.^‡
^‡ If information was not available on company website, data was based on the best information available.

CBR clinical trials and stem cell research

Successful treatments have paved the way for further research, and today, FDA-regulated clinical trials are exploring the use of a child’s own newborn stem cells for conditions that currently have no cure.³⁶ Potential treatments being evaluated today include: