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Diseases Treated

Over 28,000 caregivers have collected cord blood for Cord Blood Registry in over 3,500 hospitals located in all 50 states and more than 70 countries.

As a CBR provider, you can connect to the latest cord blood information, including patient status, education tracking, collection statistics, and much more.

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Diseases Treated with Stem Cells

Many serious or life-threatening diseases have already been treated with cord blood. The following is a list of diseases that have been treated with cord blood and other sources of the same type of stem cell, like bone marrow.

Leukemias, Lymphomas and Other Blood Cancers

Acute Biphenotypic Leukemia
Acute Lymphocytic Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Acute Undifferentiated Leukemia
Adult T Cell Leukemia/Lymphoma
Chronic Lymphocytic Leukemia (CLL)
Chronic Myelogenous Leukemia (CML)
Hodgkin's Lymphoma
Juvenile Chronic Myelogenous Leukemia (JCML)
Juvenile Myelomonocytic Leukemia (JMML)
Multiple Myeloma
Myeloid/Natural Killer (NK)
   Cell Precursor Acute Leukemia
Non-Hodgkin's Lymphoma
Prolymphocytic Leukemia
Plasma Cell Leukemia
Waldenstrom's Macroglobulinemia

Other Cancers

Brain Tumors
Ewing Sarcoma
Neuroblastoma
Ovarian Cancer
Renal Cell Carcinoma
Rhabdomyosarcoma
Small-Cell Lung Cancer
Testicular Cancer
Thymoma (Thymic Carcinoma)

Bone Marrow Failure Disorders

Aplastic Anemia (Severe)
Blackfan-Diamond Anemia
Congenital Amegakaryocytic Thrombocytopenia (CAT)
Congenital Cytopenia
Congenital Dyserythropoietic Anemia
Dyskeratosis Congenita
Fanconi Anemia
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Pure Red Cell Aplasia

Hemoglobinopathies

Beta Thalassemia Major
Sickle Cell Disease

Histiocytic Disorders

Hemophagocytic Lymphohistiocytosis (HLH)
Hemophagocytosis
Langerhans?Cell Histiocytosis (Histiocytosis X)

Myelodysplastic/Myeloproliferative Disorders

Acute Myelofibrosis
Agnogenic Myeloid Metaplasia (Myelofibrosis)
Amyloidosis
Chronic Myelomonocytic Leukemia (CMML)
Essential Thrombocythemia
Polycythemia Vera
Refractory Anemias (RA) including:
   - Refractory Anemia with Excess Blasts (RAEB)
   - Refractory Anemia with Excess Blasts in Transition (RAEB-T)
   - Refractory Anemia with Ringed Sideroblasts (RARS)

Inherited Metabolic Disorders

Fucosidosis
Gaucher Disease
Hunter Syndrome (MPS-II)
Hurler Syndrome (MPS-IH)
Krabbe Disease
Lesch-Nyhan Syndrome
Mannosidosis
Maroteaux-Lamy Syndrome (MPS-VI)
Metachromatic Leukodystrophy
Mucolipidosis II (I-cell Disease)
Neuronal Ceroid Lipofuscinosis (Batten Disease)
Niemann-Pick Disease
Sandhoff Disease
Sanfilippo Syndrome (MPS-III)
Scheie Syndrome (MPS-IS)
Sly Syndrome (MPS-VII)
Tay Sachs
Wolman Disease

Inherited Immune System Disorders

Chronic Granulomatous Disease
Congenital Neutropenia
Leukocyte Adhesion Deficiency
Severe Combined Immunodeficiencies (SCID) including:
   - Adenosine Deaminase Deficiency
   - Bare Lymphocyte Syndrome
   - Chediak-Higashi Syndrome
   - Kostmann Syndrome
   - Omenn Syndrome
   - Purine Nucleoside Phosphorylase Deficiency
   - Reticular Dysgenesis
Wiskott-Aldrich Syndrome
X-Linked Lymphoproliferative Disorder

Other Inherited Disorders

Cartilage-Hair Hypoplasia
Congenital Erythropoietic Porphyria (Gunther Disease)
DiGeorge Syndrome
Osteopetrosis

Other

Chronic Active Epstein Barr
Evans Syndrome
Multiple Sclerosis
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Thymic Dysplasia

Regenerative Medicine Clinical Trials

Neonatal Brain Injury
Cerebral Palsy
Type 1 Diabetes

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The newborn may be able to use his or her cord blood for some of the conditions on this list, but not all. In some cases, a matched sibling's stem cells would be the first choice. Some of the conditions on this list, including the regenerative medicine uses, are experimental and are in clinical trials.
Source: Medical literature and clinicaltrials.gov.
†Not eligible for CBR's Designated Treatment Program.®

Banking cord blood does not guarantee that the cells will provide a cure or be applicable for every situation. For inherited genetic conditions, the child will not be able to use his or her own stem cells. A matched sibling's stem cells would be the first choice. Ultimate use will be determined by the treating physician. Treatment for brain injury and juvenile diabetes is experimental and currently requires the use of your own cord blood. Medical treatments using family banked cord tissue are in early research and are not available today; there is no guarantee that therapies will be developed in the future.
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